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three, so it absolutely was unlikely that there was multicollinearity from the numerous linear regression types. Additionally, we performed sensitivity analyses by utilizing urinary creatinine focus (log-reworked) as a covariate as opposed to creatinine-modified urinary significant metallic concentrations and including interaction phrases concerning either toxic hefty metals (As, Cd, and Pb) or Se; none of the urinary creatinine concentration as well as the interaction terms was statistically considerable, and All round associations amongst urinary significant metals and hypertension didn't change (Tables S1 and S2).
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一般社団法人 日本プライマリ・ケア連合学会 予防医療・健康増進委員会 予防医療チーム
The main toughness of the examine was that the urine samples had get more info been gathered in seventeen communities with a variety of qualities across 4 Asian nations; this enabled an independent investigation of associations between urinary major steel concentrations and blood pressure level on the nearby amount. Review restrictions included measuring the full As concentrations on the urine samples without having speciation analysis to differentiate among publicity to toxic inorganic As and non-poisonous organic As compounds. On top of that, we assessed weighty steel publicity amounts using solitary location urine samples. To assess the systemic overall body burdens of Pb and Se, it may are actually helpful to look at their concentrations in whole blood, erythrocytes, or serum/plasma samples [71, seventy two].
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したがって、予防医療の実践においては、その介入の利益が害を上回ることを示す根拠が存在することが必要
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Desk 6 provides the outcomes of many linear regression analyses examining the associations concerning urinary weighty metallic concentrations and blood pressure level in all contributors (covariates: nation, age, sexual intercourse, and BMI). Statistically considerable associations weren't discovered involving urinary As concentrations and blood pressure. Urinary concentration of Pb was positively connected to both equally SBP and DBP, while urinary Se concentration of Se was negatively affiliated with them. All values of VIF had been below one.
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